The aim of this unit is to provide a foundation in biochemical principles with special emphasis on medical and nutritional applications. Firstly, foundations of biochemistry will be covered, including biological buffers and structures of genes, biological macromolecules such as proteins, carbohydrates, lipids and nucleic acids. Other topics covered include enzymes, bioenergetics and carbohydrate metabolism pathways, protein synthesis and modification. The clinical significance of various metabolic disorders will be discussed from a biochemical perspective.

Unit details

Study level:
Undergraduate
Credit points:
12
Unit code:
RBM2560

Prerequisites

RBM1528 - Human Physiology 2

RBF1310 - Biology 1

RCS1602 - Chemistry 1B

RCS1120 - Chemistry for Biological Sciences B

Learning Outcomes

On successful completion of this unit, students will be able to:
  1. Examine the structure and function of genes, biological macromolecules and how buffers work;  
  2. Discriminate between the structure of various proteins and review the processes by which proteins are purified and analysed;  
  3. Identify and analyse the nature and behaviour of enzymes and their reactions; and  
  4. Map and articulate metabolic pathways in bioenergetics and investigate the biochemical basis of metabolic diseases;  

Assessment

Assessment type Description Grade
Test Tests x 2 (30 min each) 20%
Laboratory Work Practical Reports x 2 (1000 words each) 30%
Examination Final Examination (2 hours) 50%

Required reading

Lehninger Principles of Biochemistry 7th ed.
Nelson, D.L., & Cox, M.M., (2017)
W.H. Freeman.

RECOMMENDED TEXT: Baynes, J.W. & Dominiczak, M.H., (2018) Medical Biochemistry 5th ed. Chatswood, N.S.W: Elsevier Health Sciences.

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