Section: Overview
Overview
Key publications
Research funding
Supervising & teaching
Career

Key details

Areas of expertise

  • Cardiovascular and kidney diseases
  • Nutrition and dietary therapy in chronic diseases prevention and treatment
  • Examining the role of the Mas receptor in endothelial dysfunction
  • Cancer

Available to supervise research students

Available for media queries

About Anthony Zulli

Dr Zulli joined Victoria University after finishing his NHMRC Peter Doherty Fellowship in 2009 (2006-2009, University of Melbourne, Austin Health). Dr Zulli's research focuses on the mechanisms that cardiovascular disease risk factors (homocysteine/cholesterol) cause endothelial dysfunction. His research has an emphasis on the nitric oxide pathway, oxidative stress and the renin-angiotensin system, and has a recent interest on reducing kidney disease caused by cancer treatments. Dr Zulli has been funded by the National Heart Foundation and NHMRC, as well as internal VU grant schemes. His pharmacology laboratory is equipped with 80 organ bath units, were he studies blood vessels from the microvasculature (60 micron diameter) to large conduit arteries (2-4mm diameter). His approved research utilises rabbits, rats, guinea pigs and mice.

His work has recently shown that the cardiovascular risk factor homocysteine could affect the efficacy of antioxidant therapy, and his collaborative work has shown that hormones released from bone can 'talk' to blood vessels during stress, improving their function.

He has published over 80 manuscripts, attracted over $1 million in funds and collaborates with local, national and international scientists.

Qualifications

  • PhD, University of Melbourne, 2009
  • GCTE, Victoria University

Key publications

Year Citation
2019 Qaradakhi, T., Gadanec, L. K., Tacey, A. B., Hare, D. L., Buxton, B. F., Apostolopoulos, V., Levinger, I., & Zulli, A. (191101). The Effect of Recombinant Undercarboxylated Osteocalcin on Endothelial Dysfunction. Calcified Tissue International, 105(5), (546-556).

doi: 10.1007/s00223-019-00600-6

2019 Smith, R. M., Rai, S., Kruzliak, P., Hayes, A., & Zulli, A. (190801). Putative Nox2 inhibitors worsen homocysteine-induced impaired acetylcholine-mediated relaxation. Nutrition, Metabolism and Cardiovascular Diseases, 29(8), (856-864).

doi: 10.1016/j.numecd.2019.05.051

2018 Bojkova, B., Kubatka, P., Qaradakhi, T., Zulli, A., & Kajo, K. (181201). Melatonin may increase anticancer potential of pleiotropic drugs. International Journal of Molecular Sciences, 19(12),

doi: 10.3390/ijms19123910

2018 Uramova, S., Kubatka, P., Dankova, Z., Kapinova, A., Zolakova, B., Samec, M., Zubor, P., Zulli, A., Valentova, V., & Kwon, T. K. (181201). Plant natural modulators in breast cancer prevention: status quo and future perspectives reinforced by predictive, preventive, and personalized medical approach. EPMA Journal, 9(4), (403-419).

doi: 10.1007/s13167-018-0154-6

2018 Tacey, A., Qaradakhi, T., Brennan-Speranza, T., Hayes, A., Zulli, A., & Levinger, I. (181004). Potential role for osteocalcin in the development of atherosclerosis and blood vessel disease. Nutrients, 10(10),

doi: 10.3390/nu10101426

2018 Opatrilova, R., Caprnda, M., Kubatka, P., Valentova, V., Uramova, S., Nosal, V., Gaspar, L., Zachar, L., Mozos, I., & Petrovic, D. (180201). Adipokines in neurovascular diseases. Biomedicine and Pharmacotherapy, 98 (424-432).

doi: 10.1016/j.biopha.2017.12.074

2018 Michalatou, M., Androutsou, M. E., Antonopoulos, M., Vlahakos, D. V., Agelis, G., Zulli, A., Qaradakhi, T., Mikkelsen, K., Apostolopoulos, V., & Matsoukas, J. (180101). Transdermal delivery of AT1 receptor antagonists reduce blood pressure and reveal a vasodilatory effect on kidney blood vessels. Current Molecular Pharmacology, 11(3), (226-236).

doi: 10.2174/1874467211666180419152036

2017 Zhang, X., Hiam, D., Hong, Y. H., Zulli, A., Hayes, A., Rattigan, S., & McConell, G. K. (171215). Nitric oxide is required for the insulin sensitizing effects of contraction in mouse skeletal muscle. Journal of Physiology, 595(24), (7427-7439).

doi: 10.1113/JP275133

2017 Kapinova, A., Stefanicka, P., Kubatka, P., Zubor, P., Uramova, S., Kello, M., Mojzis, J., Blahutova, D., Qaradakhi, T., & Zulli, A. (171201). Are plant-based functional foods better choice against cancer than single phytochemicals? A critical review of current breast cancer research. Biomedicine and Pharmacotherapy, 96 (1465-1477).

doi: 10.1016/j.biopha.2017.11.134

2017 Qaradakhi, T., Matsoukas, M. T., Hayes, A., Rybalka, E., Caprnda, M., Rimarova, K., Sepsi, M., Busselberg, D., Kruzliak, P., & Matsoukas, J. (171201). Alamandine reverses hyperhomocysteinemia-induced vascular dysfunction via PKA-dependent mechanisms. Cardiovascular Therapeutics, 35(6),

doi: 10.1111/1755-5922.12306

Research funding for the past 5 years

Please note:

  • Funding is ordered by the year the project commenced and may continue over several years.
  • Funding amounts for contact research are not disclosed to maintain commercial confidentiality.
  • The order of investigators is not indicative of the role they played in the research project.

The role of osteocalcin in blood vessel disease: A novel approach to fight blood vessels disease.
From: Rebecca L Cooper Medical Research Foundation Limited
Investigators: Aspr Itamar Levinger
For period: 2017-2018
$24,900

Supervision of research students at VU

Available to supervise research students

Available for media queries

Currently supervised research students at VU

No. of students Study level Role
3 PhD Associate supervisor
2 PhD Principal supervisor

Currently supervised research students at VU

Students & level Role
PhD (3) Associate supervisor
PhD (2) Principal supervisor

Completed supervision of research students at VU

No. of students Study level Role
1 Masters by Research Associate supervisor
1 PhD Associate supervisor

Completed supervision of research students at VU

Students & level Role
Masters by Research (1) Associate supervisor
PhD (1) Associate supervisor

Teaching activities & experience

Unit Coordinator for RBM3800: Pharmacology

Invited keynote speeches

Year Title/Description
2019

Lifestyle and coronary artery disease

Ausmed Education: The Nurse Health Coach Conference (28-29 October)

2019

Coronary artery disease and homocysteine

Ausmed Education: Chronic Disease Conference (9-10 September)

Professional memberships

  • Secretary, Australian Vascular Biology Society
  • Academic Member, Australian Atherosclerosis Society

Media appearances

28th June 2017

Chilli peppers and weight loss

ABC Melbourne Breakfast Show