Section: Overview
Key publications
Research funding
Supervising & teaching

Key details

Areas of expertise

  • Cardiovascular and kidney diseases
  • Nutrition and dietary therapy in chronic diseases prevention and treatment
  • Examining the role of the Mas receptor in endothelial dysfunction
  • Cancer

Available to supervise research students

Available for media queries

About Anthony Zulli

Dr Zulli joined Victoria University after finishing his NHMRC Peter Doherty Fellowship in 2009 (2006-2009, University of Melbourne, Austin Health). Dr Zulli's research focuses on the mechanisms that cardiovascular disease risk factors (homocysteine/cholesterol) cause endothelial dysfunction. His research has an emphasis on the nitric oxide pathway, oxidative stress and the renin-angiotensin system, and has a recent interest on reducing kidney disease caused by cancer treatments. Dr Zulli has been funded by the National Heart Foundation and NHMRC, as well as internal VU grant schemes. His pharmacology laboratory is equipped with 80 organ bath units, were he studies blood vessels from the microvasculature (60 micron diameter) to large conduit arteries (2-4mm diameter). His approved research utilises rabbits, rats, guinea pigs and mice.

His work has recently shown that the cardiovascular risk factor homocysteine could affect the efficacy of antioxidant therapy, and his collaborative work has shown that hormones released from bone can 'talk' to blood vessels during stress, improving their function.

He has published over 80 manuscripts, attracted over $1 million in funds and collaborates with local, national and international scientists.


  • PhD, University of Melbourne, 2009
  • GCTE, Victoria University

Key publications

Year Citation
2022 Ranasinghe, R., Mathai, M., & Zulli, A. (220301). A synopsis of modern - day colorectal cancer: Where we stand. Biochimica et Biophysica Acta - Reviews on Cancer, 1877(2),

doi: 10.1016/j.bbcan.2022.188699

2022 Gunarathne, L. S., Rajapaksha, I. G., Casey, S., Qaradakhi, T., Zulli, A., Rajapaksha, H., Trebicka, J., Angus, P. W., & Herath, C. B. (220101). Mas-related G protein-coupled receptor type D antagonism improves portal hypertension in cirrhotic rats. Hepatology Communications,

doi: 10.1002/hep4.1987

2022 Ridgway, H., Moore, G. J., Mavromoustakos, T., Tsiodras, S., Ligielli, I., Kelaidonis, K., Chasapis, C. T., Gadanec, L. K., Zulli, A., & Apostolopoulos, V. (220101). Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2. Computational and Structural Biotechnology Journal, 20 (2091-2111).

doi: 10.1016/j.csbj.2022.04.010

2021 Moore, G. J., Pires, J. M., Kelaidonis, K., Gadanec, L. K., Zulli, A., Apostolopoulos, V., & Matsoukas, J. M. (210701). Receptor interactions of angiotensin ii and angiotensin receptor blockersrelevance to covid-19. Biomolecules, 11(7),

doi: 10.3390/biom11070979

2021 Tacey, A., Hayes, A., Zulli, A., & Levinger, I. (210701). Osteocalcin and vascular function: is there a cross-talk?. Molecular Metabolism, 49

doi: 10.1016/j.molmet.2021.101205

2021 Liskova, A., Samec, M., Koklesova, L., Brockmueller, A., Zhai, K., Abdellatif, B., Siddiqui, M., Biringer, K., Kudela, E., & Pec, M. (210601). Flavonoids as an effective sensitizer for anti-cancer therapy: insights into multi-faceted mechanisms and applicability towards individualized patient profiles. EPMA Journal, 12(2), (155-176).

doi: 10.1007/s13167-021-00242-5

2021 McSweeney, K. R., Gadanec, L. K., Qaradakhi, T., Ali, B. A., Zulli, A., & Apostolopoulos, V. (210401). Mechanisms of cisplatininduced acute kidney injury: Pathological mechanisms, pharmacological interventions, and genetic mitigations. Cancers, 13(7),

doi: 10.3390/cancers13071572

2021 Tacey, A., Millar, S., Qaradakhi, T., Smith, C., Hayes, A., Anderson, S., Zulli, A., O'Sullivan, S., & Levinger, I. (210401). Undercarboxylated osteocalcin has no adverse effect on endothelial function in rabbit aorta or human vascular cells. Journal of Cellular Physiology, 236(4), (2840-2849).

doi: 10.1002/jcp.30048

2021 Kate, Gadanec., Qaradakhi, T., Renee, Mc. Sweeney., Ashiana, Ali., Zulli, A., & Apostolopoulos, V. (210301). Dual targeting of Toll-like receptor 4 and angiotensin-converting enzyme 2: A proposed approach to SARS-CoV-2 treatment. Future Microbiology, 16(4), (205-209).

doi: 10.2217/fmb-2021-0018

2021 Gadanec, L. K., McSweeney, K. R., Qaradakhi, T., Ali, B., Zulli, A., & Apostolopoulos, V. (210201). Can SARS-CoV-2 virus use multiple receptors to enter host cells?. International Journal of Molecular Sciences, 22(3), (1-35).

doi: 10.3390/ijms22030992

Research funding for the past 5 years

Please note:

  • Funding is ordered by the year the project commenced and may continue over several years.
  • Funding amounts for contact research are not disclosed to maintain commercial confidentiality.
  • The order of investigators is not indicative of the role they played in the research project.

The role of osteocalcin in blood vessel disease: A novel approach to fight blood vessels disease.
From: Rebecca L Cooper Medical Research Foundation Limited
Other investigators: Prof Itamar Levinger
For period: 2017-2018

Supervision of research students at VU

Available to supervise research students

Available for media queries

Currently supervised research students at VU

No. of students Study level Role
2 PhD Principal supervisor
1 PhD Associate supervisor

Currently supervised research students at VU

Students & level Role
PhD (2) Principal supervisor
PhD (1) Associate supervisor

Completed supervision of research students at VU

No. of students Study level Role
2 PhD Associate supervisor
1 PhD Principal supervisor
1 Masters by Research Associate supervisor

Completed supervision of research students at VU

Students & level Role
PhD (2) Associate supervisor
PhD (1) Principal supervisor
Masters by Research (1) Associate supervisor

Teaching activities & experience

Unit Coordinator for RBM3800: Pharmacology

Keynote and invited speeches

Year Title/Description

Lifestyle and coronary artery disease

Ausmed Education: The Nurse Health Coach Conference (28-29 October)


Coronary artery disease and homocysteine

Ausmed Education: Chronic Disease Conference (9-10 September)

Professional memberships

  • Secretary, Australian Vascular Biology Society
  • Academic Member, Australian Atherosclerosis Society

Media appearances

28th June 2017

Chilli peppers and weight loss

ABC Melbourne Breakfast Show